@font-face{font-family:PreciDisplay;src:url('/our-story-assets/display.woff2') format('woff2');font-weight:500;font-display:swap}
@font-face{font-family:PreciSans;src:url('/our-story-assets/inter.woff2') format('woff2');font-weight:100 900;font-display:swap}
:root{--purple:#6f3ccf;--deep:#4b1d82;--violet:#8b5cf6;--pale:#eee7fa;--ink:#21152f;--muted:#70667c;--line:#e8e0f0;--sans:PreciSans,Arial,sans-serif;--display:PreciDisplay,Georgia,serif;color-scheme:light}
*{box-sizing:border-box}html{scroll-behavior:smooth;scroll-padding-top:32px}body{margin:0;background:#fff;color:var(--ink);font-family:var(--sans);-webkit-font-smoothing:antialiased}a{color:var(--purple);text-underline-offset:4px;text-decoration-thickness:1px}a:hover{color:var(--deep)}a:focus-visible,summary:focus-visible,button:focus-visible{outline:3px solid var(--violet);outline-offset:5px}img{max-width:100%;height:auto;display:block}button,summary,a{touch-action:manipulation}.wrap{width:min(1180px,calc(100% - 96px));margin-inline:auto}.masthead{height:94px;margin:0 48px;display:flex;justify-content:space-between;align-items:center;border-bottom:1px solid var(--line);gap:20px}.brand{display:flex;align-items:center;gap:11px;text-decoration:none;color:var(--ink);font-size:20px;letter-spacing:-.6px}.brand img{object-fit:contain}.quiet-link{font-size:13px;text-decoration:none}.progress{position:fixed;top:0;left:0;right:0;height:3px;z-index:30;pointer-events:none}.progress span{display:block;height:100%;background:var(--purple);transform:scaleX(0);transform-origin:left}.skip{position:fixed;top:-100px;left:12px;padding:14px;background:var(--deep);color:white;z-index:50}.skip:focus{top:10px}.cover{padding-top:66px}.eyebrow{font-size:11px;line-height:1.6;letter-spacing:.13em;text-transform:uppercase;color:var(--muted);margin:0 0 26px}h1,h2,h3,p{margin-top:0}h1,h2,.closing-line{font-family:var(--display);font-weight:500;letter-spacing:-.045em}h1{font-size:clamp(64px,9vw,130px);line-height:1.02;margin-bottom:14px;color:var(--deep)}h1 span{color:var(--violet)}.subtitle{font-size:clamp(23px,2.6vw,36px);letter-spacing:-.04em;line-height:1.2;color:var(--purple);margin-bottom:36px}.opening{display:grid;grid-template-columns:1.12fr 1fr;gap:68px;max-width:1050px}.opening p{font-size:19px;line-height:1.65;margin-bottom:0}.opening strong{font-weight:650}.opening em{font-style:normal;color:var(--purple)}figure{margin:34px 0 38px}figure img{width:100%}.zoom{display:block;cursor:zoom-in;text-decoration:none}.hero-figure{margin:24px -18px 0}.hero-figure img{max-height:460px;object-fit:contain}figcaption{font-size:12px;line-height:1.65;color:var(--muted);max-width:800px;margin:14px auto 0;text-align:center}.contents{display:flex;flex-wrap:wrap;gap:12px 30px;border-block:1px solid var(--line);padding:22px 0;margin-top:36px}.contents a{font-size:12px;text-decoration:none;color:var(--deep)}.chapter{padding-top:86px;padding-bottom:66px;border-bottom:1px solid var(--line);scroll-margin-top:24px}.section-top{display:flex;gap:25px;align-items:baseline;margin-bottom:30px}.chapter-number{font-size:12px;letter-spacing:.08em;color:var(--violet)}h2{font-size:clamp(38px,4.4vw,62px);line-height:1.08;margin:0;color:var(--deep)}.copy{max-width:760px;margin-inline:auto}.copy p,.detail-body>p{font-size:18px;line-height:1.85;margin-bottom:22px}.copy p:last-child{margin-bottom:0}strong{font-weight:650}h3{font-size:25px;line-height:1.35;letter-spacing:-.035em;font-weight:550;color:var(--deep);margin:37px 0 18px}.split{display:grid;grid-template-columns:minmax(0,1.65fr) minmax(0,1fr);gap:50px;align-items:center;margin:32px 0 46px}.split figure{margin:0}.omics-key{margin:0}.omics-key>div{padding:17px 0;border-bottom:1px solid var(--line)}.omics-key>div:last-child{border-bottom:0}.omics-key dt{font-size:17px;color:var(--deep);font-weight:600;margin-bottom:7px}.omics-key dd{margin:0;font-size:14px;color:var(--muted);line-height:1.6}.mixed{grid-template-columns:minmax(0,1fr) minmax(0,1.5fr);gap:55px;margin:55px 0 0}.mixed h3{margin-top:0}.mixed p{font-size:17px}.expand{border-top:1px solid var(--line)}.chapter>.expand{margin:48px auto 0;max-width:950px}.expand summary{list-style:none;cursor:pointer;display:flex;align-items:center;gap:15px;padding:25px 0;color:var(--deep);font-size:20px;line-height:1.45;letter-spacing:-.025em}.expand summary::-webkit-details-marker{display:none}.expand summary:after{content:'+';font-size:25px;font-weight:300;margin-left:auto;min-width:20px;text-align:center}.expand[open]>summary:after{content:'−'}.summary-note{font-size:12px;font-weight:400;letter-spacing:0;color:var(--muted);margin-left:auto}.expand summary:has(.summary-note):after{margin-left:15px}.detail-body{padding:10px 0 38px;max-width:920px;margin:auto}.detail-body>p{font-size:16px;max-width:760px;margin-inline:auto}.detail-body figure{margin:30px 0}.extras{padding-top:65px;padding-bottom:15px}.extras>.eyebrow{margin-bottom:25px}.extras>.expand:last-child{border-bottom:1px solid var(--line)}.notes .detail-body>p{font-size:13px;line-height:1.8}.closing{text-align:center;padding:95px 0 105px}.closing .eyebrow{margin-bottom:24px}.closing-line{font-size:clamp(33px,4.2vw,56px);line-height:1.22;color:var(--deep);margin-bottom:30px}.text-link{display:inline-flex;align-items:center;gap:35px;padding-bottom:8px;border-bottom:1px solid var(--purple);font-size:14px;text-decoration:none}footer{border-top:1px solid var(--line);padding:29px 0 35px;display:flex;justify-content:space-between;gap:25px;align-items:center;color:var(--muted);font-size:11px}footer a{text-decoration:none}footer>a:first-child{font-size:17px;color:var(--deep)}.lightbox{border:0;padding:60px 25px 25px;width:min(1600px,96vw);max-height:94vh;overflow:auto;color:var(--ink);background:white}.lightbox::backdrop{background:#21152fd9}.lightbox img{width:100%;max-height:76vh;object-fit:contain}.close-figure{position:absolute;top:17px;right:22px;border:0;background:var(--pale);color:var(--deep);font:inherit;font-size:13px;padding:8px 13px;cursor:pointer}.lightbox-caption{font-size:13px;text-align:center;margin:15px auto 0;max-width:800px;color:var(--muted)}
@media(max-width:800px){.wrap{width:calc(100% - 44px)}.masthead{margin:0 22px;height:76px}.brand{font-size:17px}.quiet-link{font-size:11px}.cover{padding-top:42px}.eyebrow{font-size:10px;margin-bottom:20px}.opening{grid-template-columns:1fr;gap:17px}.opening p{font-size:17px}.subtitle{margin-bottom:28px}.hero-figure{margin:25px -9px 0}.contents{gap:14px 23px;margin-top:26px;padding:19px 0}.contents a{font-size:11px}.chapter{padding-top:54px;padding-bottom:45px}.section-top{gap:15px;margin-bottom:25px}.chapter-number{font-size:10px}.copy p{font-size:16px;line-height:1.85}.split,.mixed{grid-template-columns:1fr;gap:20px;margin:28px 0 35px}.omics-key{display:grid;grid-template-columns:1fr 1fr;gap:0 25px}.omics-key dt{font-size:15px}.omics-key dd{font-size:13px}.omics-key>div:nth-child(3){border-bottom:0}.mixed .copy{order:0}.mixed figure{order:1}figure{margin:25px -8px 30px}figcaption{font-size:11px;max-width:95%}h3{font-size:23px;margin-top:29px}.expand summary{font-size:17px;padding:21px 0;flex-wrap:wrap;gap:4px 12px}.summary-note{font-size:10px;margin-left:0}.expand summary:after{font-size:22px;margin-left:auto}.expand summary:has(.summary-note):after{margin-left:auto}.detail-body>p{font-size:15px}.extras{padding-top:45px}.closing{padding:65px 0}.text-link{font-size:12px;gap:20px}footer{flex-wrap:wrap;gap:17px;font-size:10px}footer span{order:3;flex-basis:100%}.lightbox{padding:55px 8px 18px;width:98vw}.lightbox-caption{font-size:11px}.notes .detail-body>p{font-size:12px}}
@media(max-width:380px){h1{font-size:54px}.brand{font-size:15px}.quiet-link{max-width:91px;text-align:right;line-height:1.4}.summary-note{display:none}.contents{gap:13px 19px}.omics-key{gap:0 15px}}
@media(prefers-reduced-motion:reduce){html{scroll-behavior:auto}*{animation:none!important;transition:none!important}}
@media print{.masthead,.contents,.progress,.lightbox,.closing,footer{display:none}.wrap{width:100%}.chapter{padding:25px 0}.expand{display:block}.expand>.detail-body{display:block}.cover{padding-top:0}h1{font-size:58px}a{color:inherit}figure{break-inside:avoid}}

.full-resolution{position:absolute;top:25px;left:22px;font-size:12px;text-decoration:none}
.omics-grid{display:grid;grid-template-columns:repeat(4,minmax(0,1fr));gap:30px;margin:0 0 42px}.omics-grid>div{border:0;padding:0}q{font-style:italic}
@media(max-width:800px){.omics-grid{grid-template-columns:1fr 1fr;gap:24px;margin-bottom:34px}}
@media(max-width:800px){h1{font-size:clamp(40px,14vw,64px)}}
.cell-opening{margin-top:50px}.cell-opening h2{font-size:clamp(32px,3.8vw,50px);margin-bottom:22px}.copy .cell-lead{font-size:22px;line-height:1.7}.living-hero{margin:35px -18px 42px}.cell-quote{margin:34px 0 38px;padding:0 0 0 25px;border-left:2px solid var(--violet)}.cell-quote p{font-family:var(--display);font-size:31px;line-height:1.3;color:var(--deep);letter-spacing:-.025em;margin-bottom:14px}.cell-quote q{font-style:normal}.cell-quote cite{font-size:12px;line-height:1.7;font-style:normal;color:var(--muted);display:block}.virtual-bridge{margin-top:50px;margin-bottom:24px}
@media(max-width:800px){.cell-opening{margin-top:38px}.copy .cell-lead{font-size:18px}.living-hero{margin:24px -8px 30px}.cell-quote{padding-left:18px;margin:28px 0}.cell-quote p{font-size:26px}.cell-quote cite{font-size:11px}.virtual-bridge{margin-top:38px}}
.model-scope{margin-top:30px}.model-entry{margin-top:34px}.table-scroll{max-width:100%;overflow-x:auto;margin:10px 0 25px}.reference-table{border-collapse:collapse;width:100%;font-size:14px;line-height:1.65;min-width:520px}.reference-table th,.reference-table td{text-align:left;vertical-align:top;padding:16px;border-bottom:1px solid var(--line)}.reference-table th{color:var(--deep);font-weight:600}.reference-table th:first-child{padding-left:0;width:20%}.reference-table thead{font-size:12px;color:var(--muted)}.perturbation-key{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:35px;margin:15px 0 38px}.perturbation-key dt,.glossary-list dt{font-weight:600;color:var(--deep);margin-bottom:10px}.perturbation-key dd{margin:0;font-size:15px;line-height:1.75}.glossary-list{margin:0}.glossary-list>div{display:grid;grid-template-columns:150px 1fr;gap:25px;border-bottom:1px solid var(--line);padding:18px 0}.glossary-list dt{font-size:15px;margin:0}.glossary-list dd{margin:0;font-size:15px;line-height:1.7}
@media(max-width:800px){.perturbation-key{grid-template-columns:1fr;gap:24px}.perturbation-key dd{font-size:14px}.glossary-list>div{grid-template-columns:1fr;gap:6px}.glossary-list dd{font-size:14px}.reference-table{font-size:13px}.reference-table th,.reference-table td{padding:12px}}
.reader-hook{margin:38px 0 0;max-width:780px}.reader-hook p{font-size:21px;line-height:1.65;margin-bottom:18px}.reader-hook p:last-child{color:var(--muted);font-size:18px}.copy .thesis{margin-block:32px;padding-left:23px;border-left:2px solid var(--violet);font-size:23px;line-height:1.55;color:var(--deep)}.closing-copy{font-size:17px;line-height:1.8;color:var(--muted);margin-bottom:32px}.cover h1{font-size:clamp(64px,8.8vw,116px);max-width:1000px}.cover .subtitle{font-size:clamp(20px,2.4vw,29px);line-height:1.4;letter-spacing:-.025em}.chapter .living-hero{margin-top:30px}
@media(max-width:800px){.cover h1{font-size:clamp(46px,12.8vw,74px)}.reader-hook{margin-top:28px}.reader-hook p{font-size:18px;line-height:1.7}.reader-hook p:last-child{font-size:16px}.copy .thesis{font-size:20px;padding-left:18px}.closing-copy{font-size:15px}}